My Projects
Projects I have worked on recently.
Chasing myelin — how an autism hypothesis about supply became one about timing
Myelin is the fatty insulation around axons, and the prefrontal cortex is the last part of the brain to get it. That makes a tempting hypothesis: if the machinery for making it is constitutionally weak, the last place to be insulated should be the first place to fail — which happens to be the region whose functions look most like the ones disrupted in autism. This is the log of testing that idea on public data, the two reframings the data forced, and the sharper question that came out the other side.
Mon Sep 21 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

Bendy bodies, restless minds — a correlation we can measure but cannot yet explain
People with unusually flexible joints get migraines about twice as often as everyone else, and are diagnosed with ADHD around five times as often. The association is real, replicated, and partly genetic. This is the log of an attempt to find the mechanism behind it — the elegant explanation that turned out to be wrong, the things we could rule out, and the one thread still worth pulling.
Thu Sep 10 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

Where is the 'blueprint' in the C. elegans connectome?
A worm's genome is far too small to store its ~7,000 wiring connections one by one — yet the wiring is nearly the same in every animal. So where is the information that specifies it? This is the log of a systematic hunt: a dozen candidate 'hidden codes' tested and ruled out, and the surprisingly simple thing that was left standing.
Wed Jul 01 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

Tier4 Substrate Anatomy — a whole-cell electrical substrate, rendered from code
An interactive 3D anatomy of the C. elegans Tier4 whole-cell electrical substrate. Every channel, receptor, pump, transporter, gap junction, and ion compartment actually present in the Brian2 model is rendered 1:1 from code with an honest ON / default-OFF / ORPHANED / NOT-INTEGRATED status.
Fri Jun 19 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

Antibiotic Resistance — Mutation Trajectory Prediction
Predicting the next resistance mutation given an ordered evolution history, over ALEdb plus CARD plus deep mutational scanning data. A LightGBM + autoregressive transformer + reranker stack lifts canonical-AMR top-3 from 0.17 to 0.403 across 14 drug classes.
Tue May 12 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

cfDNA Cancer Detection — A Cross-Cohort Recovery Story
Cell-free DNA methylation cancer detection over the Loyfer atlas. Cross-cohort AUROC on GSE122126 went from 0.217 (below random, model inverted) to 0.850 across four of five cancer types. The four mechanisms that closed the gap, and the literature check that showed they're not novel.
Tue May 12 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

Clinical Trial Failure Prediction
Phase-3 trial outcome prediction over the AACT clinical trials database, with a leakage audit that proved the headline number is signal, not label encoding. Audited AUROC 0.8603. The audit methodology is the part worth carrying forward, not the model.
Tue May 12 2026 00:00:00 GMT+0000 (Coordinated Universal Time)
Anesthesia Pipeline — Network-State Validation
Network-state validator for volatile anesthesia on a substrate-agnostic LIF integrator. Predicts EC50s, mutant magnitudes, and Eger non-immobilizer specificity from literature-grounded multi-target perturbation profiles across three independent organism calibrations (worm Cook 2019, fly Winding 2023, mouse generic random graph).
Wed Apr 15 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

ARC Prize 2025
Ongoing attempt at the ARC-AGI benchmark — a pipeline-based approach to program synthesis, symmetry reasoning, and abstraction discovery.
Sat Nov 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

C. elegans Connectomics + Transcriptomics
Multi-modal analysis asking how much of local wiring in a small nervous system is determined by topology vs. gene expression.
Mon Sep 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

NeurIPS Polymer Prediction
Kaggle competition for predicting polymer properties from SMILES-style representations — a multi-phase hybrid pipeline combining gradient-boosted and deep models.
Tue Jul 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

Stanford RNA 3D Folding
Kaggle competition entry for predicting RNA 3D structure from sequence — a pipeline + evaluation stack using TM-align for structural scoring.
Sun Jun 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

AI vs. Human Art Classification
A deep-learning classifier that distinguishes AI-generated from human-made artwork, with interpretability via Grad-CAM, t-SNE, and PCA.
Tue Apr 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

HSDE — Hybrid Symbolic Discovery Engine
Neural-symbolic reasoning prototypes: a recursive CA + attention + symbolic hybrid, and an Enhanced Symbolic Discovery Engine targeting AIME / SAT / GSM8K.
Sat Jun 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time)
OnServe Tennis — Website
Website for OnServe Tennis, built in React. An earlier full-stack project from before I moved primarily into ML research.
Wed Jun 22 2022 00:00:00 GMT+0000 (Coordinated Universal Time)
Code-OCR
An OCR tool for interpreting source code images (.jpg, .png) and outputting machine-readable text — an early exploration of vision-to-code conversion.
Tue Mar 15 2022 00:00:00 GMT+0000 (Coordinated Universal Time)
GG Tennis Academy — Website
Website for GG Tennis Academy. An early web-development project from before I moved primarily into ML research.
Tue Mar 15 2022 00:00:00 GMT+0000 (Coordinated Universal Time)
Carbon Emissions Tracker — Florida Hacks with IBM
Hackathon project for Florida Hacks with IBM — a carbon emissions tracking app to help users quantify and reduce their footprint.
Wed Aug 25 2021 00:00:00 GMT+0000 (Coordinated Universal Time)