Connectomics

A new dimension to access content of this website

Halothane vs hexafluoroethane network-state response on the C. elegans Cook 2019 connectome — anesthetic pushes command-interneuron firing into quiescent regime, non-immobilizer does not, across four orders of magnitude in dose.

Anesthesia Pipeline — Network-State Validation

Connectome-constrained network-state validator for C. elegans anesthesia. Predicts immobilization EC50, mutant phenotypes, and Eger non-immobilizer specificity from literature-grounded multi-target perturbation profiles applied to a 300-neuron Brian2 brain.

Illustrated C. elegans worm with colored neural-network overlay — Rohit Ravi's connectomics + transcriptomics project

C. elegans Connectomics + Transcriptomics

Multi-modal analysis asking how much of local wiring in a small nervous system is determined by topology vs. gene expression.