Bioinformatics
A new dimension to access content of this website
Antibiotic Resistance — Mutation Trajectory Prediction
Predicting the next resistance mutation given an ordered evolution history, over ALEdb plus CARD plus deep mutational scanning data. A LightGBM + autoregressive transformer + reranker stack lifts canonical-AMR top-3 from 0.17 to 0.403 across 14 drug classes.
Tue May 12 2026 00:00:00 GMT+0000 (Coordinated Universal Time)
Bendy bodies, restless minds — a correlation we can measure but cannot yet explain
People with unusually flexible joints get migraines about twice as often as everyone else, and are diagnosed with ADHD around five times as often. The association is real, replicated, and partly genetic. This is the log of an attempt to find the mechanism behind it — the elegant explanation that turned out to be wrong, the things we could rule out, and the one thread still worth pulling.
Thu Sep 10 2026 00:00:00 GMT+0000 (Coordinated Universal Time)